Barcelona drew 1-1 at Valencia after Real Madrid lost 1-0 away to Alaves, allowing Sevilla to go top of La Liga with a 2-1 home win over Celta Vigo on Sunday. Here are five talking points from the weekend's La Liga action.
News of all that's transpired on and off the football field.
Mourinho's tinkerings meant a first start of the season for midfielder Scott McTominay, playing on the right of a three-man defence, while Anthony Martial played instead of the dropped Alexis Sanchez. On this evidence, more changes may be needed when United take on Valencia in the Champions League on Tuesday.
Ferrari's Fernando Alonso thrilled home fans by winning an incident-packed European Grand Prix in Valencia on Sunday to take the overall championship lead and become Formula One's first repeat winner of the season.
Valencia are expecting a counter-attacking team such as Real Madrid rather than a possession-hungry side like Barcelona when they host Paris St Germain in the Champions League on Tuesday, coach Ernesto Valverde said.
Captain Paul Pogba produced an outstanding performance garnished by two goals to help Manchester United to a resounding 3-0 win at Swiss debutants Young Boys Bern in their Champions League Group H opener on Wednesday.
Valencia ended a miserable week on a high when they came from behind to snatch a 3-2 win at struggling 10-man Deportivo La Coruna that lifted them to fifth in La Liga on Saturday.
David Ferrer toppled Philipp Kohlschreiber in a thrilling five-hour marathon decider as Spain roared back from 2-1 down in their Davis Cup tie against Germany to reach the semi-finals on Sunday.
Germany's Jan-Lennard Struff and Tim Puetz pulled off a shock 6-3, 6-4, 3-6, 6-7(4), 7-5 win over Spain's Feliciano Lopez and Marc Lopez to give Germany a 2-1 lead in their Davis Cup quarter-final on Saturday.
Victory meant Nadal set the record for the longest Davis Cup winning streak in combined singles and doubles rubbers with 23 matches in a row.
Real Madrid put themselves on course for a place in the King's Cup semi-finals after securing a 2-0 first leg victory over Valencia at the Bernabeu on Tuesday.
Manchester City progressed to the knockout stages of the Champions League from Group F on Tuesday after twice coming from behind to draw 2-2 with Olympique Lyonnais, a team Pep Guardiola hailed as one of the toughest he has ever faced.
News of all that's transpired on and off the football field
World number two Rafael Nadal has been named in Spain's squad for their Davis Cup World Group quarter-final against Germany in Valencia next month.
News of all that's transpired on and off the football field
Valencia moved towards a place in the King's Cup quarter-finals and a possible meeting with Real Madrid when Dani Parejo and substitute Roberto Soldado struck in a 2-0 win at Osasuna in their last 16, first leg on Tuesday.
Manchester United stretched their lead at the top of the Premier League to five points after in-form Antonio Valencia struck nine minutes from time to set up a 2-0 win at relegation-threatened Blackburn Rovers on Monday.
Photos of the World Cup match between France and Ecuador
Valencia have agreed to appoint Ernesto Valverde to replace Mauricio Pellegrino as their new coach until the end of the season, the Spanish club said on Monday.
World No 5 David Ferrer beat unseeded Ukrainian Alexandr Dolgopolov 6-1 3-6 6-4 to win the Valencia Open for the third time on Sunday, claiming his sixth ATP World Tour title this year.
Milos Raonic and John Isner were knocked out of the Valencia Open by lower-ranked opponents on Wednesday, denting their chances of clinching one of two remaining berths at next month's World Tour finals in London.
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'I can't comment on speculation. I don't bet and I don't do the lottery - it's not my way'
Italian Ranieri takes his side, currently bottom of the Premier League, to United on Saturday and said he is looking forward to renewing his friendship with the man who replaced him as Chelsea manager in 2004.
Barcelona were held to a 1-1 draw at relegation-fighting Las Palmas on Thursday in an unexpected setback that left them with a five-point lead in La Liga ahead of their top-of-the-table showdown with Atletico Madrid this weekend.
Real Madrid's reliance on their talisman Cristiano Ronaldo was more evident than ever on Tuesday as the Spanish and European champions meekly lost 1-0 at Espanyol in La Liga.
The 46-year-old has been hired to fill the sizeable void left by the departure of Frenchman Arsene Wenger who had been at the Arsenal helm since 1996.
A Neymar double and a clinical finish from Luis Suarez handed Barcelona a comfortable 3-0 victory over BATE Borisov that put them on the verge of qualifying for the last 16 of the Champions League for the 12th consecutive season.
The shock of the season saw Barca suffer their first league loss since going down 2-0 to Malaga on April 8, 2017, ending an incredible, record-breaking sequence that had lasted 43 games.
Real Madrid's stuttering season continued as they were reduced to 10 men and then slumped to an 11th La Liga defeat of the campaign by going down 3-1 at Real Sociedad.
Summary of sports events and persons who made news on Wednesday
News of all that's transpired on and off the football field
Giampaolo Pazzini struck an 89th-minute equaliser on his Levante debut to earn his side a deserved 2-2 draw against struggling giants Real Madrid on Saturday.
Alexandre Lacazette's free-kick sent Arsenal into the Europa League semi-finals with a comfortable 1-0 win away over Napoli, while Chelsea beat Slavia Prague 4-3 in a roller-coaster game, helped by a Pedro brace.
News of all that's transpired on and off the football field
Lionel Messi scored a hat-trick as Barcelona clinched a 25th La Liga title on Sunday after winning 4-2 at Deportivo La Coruna despite throwing away a two-goal lead in a thrilling game which also confirmed Depor's relegation.
Holders Barcelona reached the King's Cup semi-finals with a 2-0 win over Espanyol on Thursday to overcome a first-leg deficit on a night when new signing Philippe Coutinho made his debut.
News of all that's transpired on and off the football field
Real Madrid suffered a humiliating 2-1 home defeat by Leganes on Wednesday to exit the King's Cup at the quarter-final stage on away goals.
Barcelona have strengthened their defence and found a replacement for Eric Abidal by sealing an agreement with Valencia to sign Spain fullback Jordi Alba on a five-year contract.